Use of large doses of capsaicin (hot pepper) cream has been found to help the pain of neuropathy (a condition of the peripheral nerves causing weakness and numbness) and CRPS. Study by researcher Linda Bartoshuk found: "Sensory neuropathies are associated with many diseases. Pain from these disorders can produce greater disability than the primary disease processes themselves. Currently available therapies are limited. However, the intermittent application of large-dose topical capsaicin may provide significant pain relief [and] decrease chronic analgesic dependence..."